The Santosham Best Actress Award is given by the Santosham Film magazine as part of its annual Santosham Film Awards for Telugu films.
The award was first given to Asin Thottumkal in 2003. Here is a list of the award winners and the films for which they won.
| Year | Actor | Film | Ref |
|---|---|---|---|
| 2010 | Anushka Shetty | Vedam | [1] |
| 2009 | Anushka Shetty | Arundhati | [2] |
| 2008 | Ileana D'Cruz | Jalsa | [3] |
| 2007 | Bhumika Chawla | Anasuya | [4] |
| 2006 | Genelia D'Souza | Bommarillu | [5] |
| 2005 | Charmme Kaur | Anukokunda Oka Roju | [6] |
| 2004 | Trisha Krishnan and Jyothika Sadanah | Varsham and Mass | [7] |
| 2003 | Asin | Shivamani 9848022338 | [8] |